The overall survival was 68.78 months in LE group compared with 74.81 months in TME group ( p = 0.964). Conclusion: Our results of a small sample size showed that local excision ± chemoradiation is a rather safe method for early rectal cancer compared with gold standard treatment. In addition, better bowel function is preserved with less ...
DetailsPerioperative clinical and histopathological outcomes are presented in Table 2.Conversion to an open approach (either a Pfannenstiel incision or a median laparotomy) was significantly more common in the Da Vinci cohort (4/18 vs. 0/33, p = 0.012).Reasons for conversion to a Pfannenstiel incision were bulky tumors (n = 2) and insufficient exposure …
DetailsBackground: The objective of this pilot study was to evaluate the feasibility and safety of natural orifice endoscopic transanal total mesorectal excision (TME) with laparoscopic assistance in a cohort study of five patients with stage I and IIA rectal cancer. Methods: Five eligible patients with node-negative rectal cancer located 4-12 cm from the anal verge …
DetailsTME was considered to the most important progress in surgery for rectal cancer in the last two decades. With the application of TME, the local recurrence decreased to 6 to 12%, and 5-year survival rate improved by 53–87% ( 6 – 9 ). Hence, TME has gradually become a standard component of radical surgery in rectal cancer treatment ( 10 ).
DetailsThis prospective randomized trial compared endoluminal locoregional resection (ELRR) by transanal endoscopic microsurgery versus laparoscopic TME in the treatment of patients with small non-advanced low rectal cancer. Patients with rectal cancer staged clinically as cT2 N0 M0, histological grade G1–2, with a tumour less than 3 cm in …
DetailsDOI: 10.1016/s1470-2045(20)30555-6 Corpus ID: 228101807; Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) versus preoperative chemoradiotherapy, TME, and optional adjuvant chemotherapy in locally advanced rectal cancer (RAPIDO): a randomised, open-label, phase 3 trial.
DetailsAim of this study was to evaluate functional outcomes of transanal total mesorectal excision (TaTME) in comparison to conventional laparoscopic approach (LaTME) in terms of low anterior resection syndrome (LARS). Methods Forty-six patients who underwent total mesorectal excision for low rectal cancer between 2013 and 2017 …
DetailsRectal adenocarcinoma is a relatively common malignancy with approximately 40,000 people being diagnosed annually in the USA.1 The surgical treatment of this disease has evolved considerably over the past 30 years. As highlighted by the work of Heald,2 the surgical technique of total mesorectal excision (TME) greatly impacts oncologic …
DetailsWith the evolution of technology, minimally invasive options are readily available, making laparoscopic, robotic and transanal approaches valid alternatives to open total mesorectal excision (TME). The current debate is centered on which approach or combination would yield the best results to patients requiring radical resection for rectal cancer.
DetailsImportance Proponents of novel transanal total mesorectal excision (TME) suggest the procedure overcomes the technical and oncologic challenges of conventional approaches for treating rectal cancer. Recently, however, there has been controversy regarding the oncologic safety of the procedure. Objective To assess the association of …
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DetailsThis first report, describing transanal TME (TaTME), aroused great interest because it demonstrated the feasibility of a hybrid NOTES procedure that could be applied to challenging real-life situations, such as the difficult TME for mid and distal rectal cancer.
DetailsT1 - Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) versus preoperative chemoradiotherapy, TME, and optional adjuvant chemotherapy in locally advanced rectal cancer (RAPIDO) T2 - a randomised, open-label, phase 3 trial. AU - RAPIDO collaborative investigators. AU - Bahadoer, Renu R. AU - Dijkstra, Esmée A
DetailsRadical rectal cancer resection, namely total mesorectal excision (TME), is the cornerstone of the treatment of resectable rectal cancer. In combination with chemotherapy and radiation treatment (CRT), complete TME with negative resection margins is associated with sustained local and systemic control even in locally advanced …
Details28. Lacy AM, Tasende MM, Delgado S, Fernandez-Hevia M, Jimenez M, et al. Transanal total mesorectal excision for rectal cancer: outcomes after 140 patients. J Am Coll Surg 2015;221:415-23. DOI PubMed; 29. Penna M, Hompes R, Arnold S, Wynn G, Austin R, et al. Transanal total mesorectal excision. international registry results of the first 720 cases.
DetailsUrinary and sexual dysfunctions are recognized complications after surgery for rectal cancer. Since the introduction of total mesorectal excision (TME), oncology outcomes and genitourinary functional preservation rate have greatly improved.1 The conventional open TME is associated with 0–12% patient urinary dysfunction and …
DetailsWasmuth HH, Færden AE, Myklebust T, et al. Transanal total mesorectal excision for rectal cancer has been suspended in Norway. Br J Surg 2020;107:121-30. Penna M, Hompes R, Arnold S, et al. Transanal Total Mesorectal Excision: International Registry Results of the First 720 Cases. Ann Surg 2017;266:111-7.
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